One of the most common questions we receive at Serendipity Lifestyle & Wellness Spa is the difference between Botox and filler. Botox is a brand of “neuromodulator,” which relaxes the underlying muscles that cause wrinkles to form. Conversely, filler helps lift and “fill” areas that have lost volume or show wrinkles. Most of the time, it is a combination of both of these that truly produce the most radiant results.